PEER-REVIEWED · PUBLISHED IN mSYSTEMS · ASU + FLORÉ STUDY

Respecting
gut diversity.
Naturally.

Autistic microbiomes are different — not broken. 62% of participants saw improvement when their gut got the specific support it needed. Personalized probiotics built from your data, not a one-size-fits-all guess.

296
Autistic participants enrolled
62%
Reported overall improvement
94.5%
Model accuracy identifying autistic microbiomes
p<0.05
Statistically significant GI symptom reduction
IMPROVEMENT REPORTED BY AREA
GI Comfort
52%
Cognition
50%+
Language
50%+
Social
46%
Behavior
44%
Source: Adams, Krajmalnik-Brown et al., mSystems 2024. Parent Global Impressions (PGIA), n=170 completers.

Diversity is strength — in a microbiome, in a community, and in a mind.

We don't try to make your gut “normal.” We study what your unique microbiome actually needs to thrive — then we build exactly that. The same way nature works: not by uniformity, but by supporting what's already there.

EVIDENCE BASED

THE CLINICAL EVIDENCE

Real data. Real families. Real improvement.

Published in mSystems (2024) by researchers at Arizona State University and Floré. The largest study of its kind on personalized probiotics and autism. Read the full paper · Our deep dive

296
Autistic participants enrolled
170 completed the full study
62%
Reported symptom improvement
Per Parent Global Impressions (PGIA)
0.945
Model accuracy (AUC)
ML classification of autistic vs. neurotypical microbiome
123
Neurotypical controls
Age-matched comparison group

Adams, Krajmalnik-Brown et al. “Precision synbiotics increase gut microbiome diversity and improve gastrointestinal symptoms in a pilot open-label study for autism spectrum disorder.” mSystems, 2024. PMC11097633

WHAT THE RESEARCH FOUND

What happened when gut microbiomes got the right support.

50%+
Cognition and clarity
More than half of participants reported improvements in cognitive function when their microbiome diversity increased.
50%+
Language and communication
Improvements in both receptive and expressive language reported by families. The gut-brain axis at work.
52%
GI comfort
Statistically significant reduction in gastrointestinal symptoms (GSRS, p<0.05). Comfort is foundational.
p<0.05
Microbiome diversity grew
Shannon index, richness, and evenness all significantly increased. A more diverse microbiome is a more resilient one.
62%
Overall wellbeing
Per PGIA: 62% some improvement, 30% no change, only 6% worsened. Personalized support works.
Custom
Precision, not guesswork
Each formula is built from a microbiome analysis of up to 2,300 species. Your microbiome is unique — your support should be too.

BUILT FOR NEURODIVERSITY

Different brains. Different guts. Same respect.

The gut-brain connection doesn't fit into neat diagnostic boxes. Whether you're autistic, ADHD, managing sensory processing, or navigating the overlap — a thriving gut is the foundation.

Autism spectrum
GI issues affect up to 90% of autistic people. Supporting gut diversity can ripple into comfort, cognition, and daily life.
ADHD and focus
Emerging research connects gut microbiome diversity to attention regulation and executive function. Same science, different expression.
Sensory processing
Sensory sensitivities often coexist with GI distress. When the gut stabilizes, the nervous system can too.
Anxiety and mood
26% of study participants met the threshold for anxiety. The gut produces 90% of your serotonin — a healthy gut matters.

TWO PATHS TO START

Start wherever you are.
We'll meet you there.

NO LAB WORK NEEDED

Tell us what's going on

Answer questions about GI symptoms, diet, sensory sensitivities, and daily challenges. We'll build a personalized formula from there — no stool sample required.

Start the assessment
HAVE LAB RESULTS?

Upload your report

Microbiome test, GI panel, stool analysis — upload whatever you have from your provider. We'll formulate a precision blend from your actual data.

Upload a report

HOW IT WORKS

Simple process.
Precise support.

The same science from the ASU study, personalized and shipped to your door.

01

Share the details

Upload a lab report or answer our assessment. We capture diet, GI patterns, sensory details, and health history to understand the full picture.

About 5 minutes
02

We formulate

Our team builds a custom probiotic + prebiotic blend targeting specific microbiome gaps. Up to 2,300 species analyzed. Nothing generic.

Precision blend
03

Delivered to your door

Your personalized formula arrives ready to go. Track progress, adjust the formula as things evolve, and watch things shift.

Ongoing support

Precision probiotics vs. generic supplements

FeatureAutism ProbioticsGeneric Probiotics
Formulated from microbiome data✓✗
Backed by autism clinical study✓✗
Up to 2,300 species analyzed✓✗
Formula evolves with progress✓✗
No stool sample required✓—
Works from labs or symptoms✓✗
One-size-fits-all approach✗✓

Diversity. Growth. Real effect.

Personalized probiotics that respect how you're built. Backed by the science, made for you.

Questions about your order, your formula, or anything else?
Reach us at support@flore.com